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mh7a (fls in human ra) cells  (Procell Inc)

 
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    Procell Inc mh7a (fls in human ra) cells
    Mh7a (Fls In Human Ra) Cells, supplied by Procell Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mh7a+%28fls+in+human+ra%29+cells/pm40185320-53-0-16?v=Procell+Inc
    Average 90 stars, based on 1 article reviews
    mh7a (fls in human ra) cells - by Bioz Stars, 2026-08
    90/100 stars

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    CP-25 down-regulated excessive synoviocyte activation by decreasing GRK2-mediated β2-AR desensitization. <t>MH7A</t> (A,B) proliferation (1 nM: t = 1.067, P < 0.05; 0.1 μM: t = 3.584, P < 0.01; 1 μM: t = 5.768, P < 0.01; 10 μM: t = 5.685, P < 0.01), (C,E) migration (0.1 μM: t = 5.268, P < 0.01; 1 μM: t = 6.141, P < 0.01; 10 μM: t = 6.070, P < 0.01), and (D,F) invasion (0.1 μM: t = 2.514, P < 0.05; 1 μM: t = 5.477, P < 0.01; 10 μM: t = 5.691, P < 0.01). Data are expressed as the mean ± SD. ## P < 0.01 vs. control; ∗ P < 0.05, ∗∗ P < 0.01 vs. TNF + ISO. The results are representative of at least three independent experiments. (G–I) Expression of β2-AR ( t = –12.745, P < 0.01) and GRK2 ( t = 5.986, P < 0.01). The results are representative of at least three independent experiments and data are expressed as the mean ± SD. ∗∗ P < 0.01 vs. TNF.
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    CP-25 down-regulated excessive synoviocyte activation by decreasing GRK2-mediated β2-AR desensitization. MH7A (A,B) proliferation (1 nM: t = 1.067, P < 0.05; 0.1 μM: t = 3.584, P < 0.01; 1 μM: t = 5.768, P < 0.01; 10 μM: t = 5.685, P < 0.01), (C,E) migration (0.1 μM: t = 5.268, P < 0.01; 1 μM: t = 6.141, P < 0.01; 10 μM: t = 6.070, P < 0.01), and (D,F) invasion (0.1 μM: t = 2.514, P < 0.05; 1 μM: t = 5.477, P < 0.01; 10 μM: t = 5.691, P < 0.01). Data are expressed as the mean ± SD. ## P < 0.01 vs. control; ∗ P < 0.05, ∗∗ P < 0.01 vs. TNF + ISO. The results are representative of at least three independent experiments. (G–I) Expression of β2-AR ( t = –12.745, P < 0.01) and GRK2 ( t = 5.986, P < 0.01). The results are representative of at least three independent experiments and data are expressed as the mean ± SD. ∗∗ P < 0.01 vs. TNF.

    Journal: Frontiers in Pharmacology

    Article Title: A Modified Compound From Paeoniflorin, CP-25, Suppressed Immune Responses and Synovium Inflammation in Collagen-Induced Arthritis Mice

    doi: 10.3389/fphar.2018.00563

    Figure Lengend Snippet: CP-25 down-regulated excessive synoviocyte activation by decreasing GRK2-mediated β2-AR desensitization. MH7A (A,B) proliferation (1 nM: t = 1.067, P < 0.05; 0.1 μM: t = 3.584, P < 0.01; 1 μM: t = 5.768, P < 0.01; 10 μM: t = 5.685, P < 0.01), (C,E) migration (0.1 μM: t = 5.268, P < 0.01; 1 μM: t = 6.141, P < 0.01; 10 μM: t = 6.070, P < 0.01), and (D,F) invasion (0.1 μM: t = 2.514, P < 0.05; 1 μM: t = 5.477, P < 0.01; 10 μM: t = 5.691, P < 0.01). Data are expressed as the mean ± SD. ## P < 0.01 vs. control; ∗ P < 0.05, ∗∗ P < 0.01 vs. TNF + ISO. The results are representative of at least three independent experiments. (G–I) Expression of β2-AR ( t = –12.745, P < 0.01) and GRK2 ( t = 5.986, P < 0.01). The results are representative of at least three independent experiments and data are expressed as the mean ± SD. ∗∗ P < 0.01 vs. TNF.

    Article Snippet: The human RA fibroblast-like synoviocyte (FLS) cell line, MH7A, was purchased from the China Center for Type Culture Collection.

    Techniques: Activation Assay, Migration, Control, Expressing